Unusual Fundus Autofluorescence Appearance in a Patient with Hydroxychloroquine Retinal Toxicity

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Unusual Fundus Autofluorescence Appearance in a Patient with Hydroxychloroquine Retinal Toxicity

PURPOSE To report an unusual fundus autofluorescence aspect in a patient with suspected hydroxychloroquine retinal toxicity. METHOD Case report of an unusual presentation of a patient treated for 9 consecutive years with a therapeutically recommended dose of hydroxychloroquine. RESULT We report the case of a 53-year-old Caucasian female treated with 400 mg hydroxychloroquine for rheumatoid ...

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Fundus autofluorescence and mfERG for early detection of retinal alterations in patients using chloroquine/hydroxychloroquine.

PURPOSE To evaluate and compare the value of fundus autofluorescence (FAF) imaging and multifocal electroretinography (mfERG) in early detection of retinal alterations in patients using chloroquine/hydroxychloroquine (CQ/HCQ). METHODS FAF imaging was performed in a consecutive series of 25 patients with long-term CQ or HCQ treatment (duration, >1 year), with or without visual disturbances. In...

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Fundus autofluorescence applications in retinal imaging

Fundus autofluorescence (FAF) is a relatively new imaging technique that can be used to study retinal diseases. It provides information on retinal metabolism and health. Several different pathologies can be detected. Peculiar AF alterations can help the clinician to monitor disease progression and to better understand its pathogenesis. In the present article, we review FAF principles and clinic...

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Fundus autofluorescence imaging of retinal dystrophies

Fundus autofluorescence (FAF) is a non-invasive imaging technique that enables the visualization of lipofuscin changes in the retinal pigment epithelium. This study aims to illustrate the spectrum of FAF changes in a variety of retinal dystrophies. For this purpose, we examined patients with retinal dystrophies such as Stargardt disease, Best vitelliform macular dystrophy, and retinal dystrophi...

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Retinal toxicity in long term hydroxychloroquine treatment.

OBJECTIVE To report clinical experience from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) who were receiving recommended doses of hydroxychloroquine for more than six years, and were monitored for evidence of hydroxychloroquine related retinopathy every six months. METHODS A prospective (and continuing) evaluation was made of the potential retinal toxicity of...

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ژورنال

عنوان ژورنال: Case Reports in Ophthalmology

سال: 2015

ISSN: 1663-2699

DOI: 10.1159/000433417